Cleo Review 2026

Name: Cleo
Brand: Cleo
Price: 50 USD
Availability: InStock

Honest pros, cons, and verdict on this automation & workflows tool

✅ Aims to consolidate deterioration detection, sepsis prediction, and capacity management into a single acute-care-focused platform, potentially reducing the need to procure and integrate multiple point solutions

Starting Price

~$50,000–$80,000 (unconfirmed estimate)

Free Tier

What is Cleo?

AI-powered clinical decision support platform for acute care hospitals, providing real-time patient deterioration detection, sepsis prediction, and workflow optimization to improve outcomes and reduce clinician burnout.

Cleo is an enterprise-priced clinical decision support (CDS) platform in the Healthcare AI category, targeting acute care hospitals with AI-driven deterioration detection, sepsis prediction, and capacity management. Pricing is custom per facility and not publicly disclosed; based on comparable platforms in this category (such as Viz.ai and Qventus), costs likely fall in the range of $50,000–$200,000+ per facility per year depending on bed count and modules, though these figures are unconfirmed estimates and should not be treated as actual Cleo pricing. No free or self-serve tier is available.

The platform is built specifically for acute care environments including emergency departments, intensive care units, and inpatient hospital floors. It uses machine learning models trained on clinical data to help care teams identify patients at risk of deterioration, predict sepsis onset, and streamline clinical workflows in high-acuity settings.

Key Features

✓Early Warning System for Patient Deterioration: Claims to continuously monitor physiological trends from EHR data to identify patients at risk of clinical deterioration before traditional scoring systems trigger alerts. Unlike Epic's built-in Sepsis Model, which focuses on sepsis scoring alone, this module targets broader clinical deterioration patterns.

✓Sepsis Prediction: Analyzes combinations of vital signs, lab values, and clinical documentation to flag patients meeting or approaching sepsis criteria for earlier intervention. Vendor claims this outperforms static rule-based sepsis screens, but no peer-reviewed validation is publicly available.

✓EHR Integration: Claims connectivity with major electronic health record systems including Epic and Cerner to ingest real-time patient data without disrupting existing clinical workflows. Integration depth and compatibility should be verified directly with the vendor.

✓Capacity Management: Provides insights into patient flow, bed availability, and staffing needs. Unlike Qventus, which focuses primarily on operational throughput and surgical scheduling, Cleo positions this as part of a unified clinical-and-operational surveillance platform.

✓Configurable Alert Thresholds: Reportedly allows clinical informatics teams to adjust model sensitivity and alert frequency to balance detection accuracy against alert fatigue for their specific facility.

✓Explainable Risk Scores: Described by the vendor as displaying contributing factors behind each risk score and alert, giving clinicians transparency into the AI's reasoning to support informed clinical judgment.

Pricing Breakdown

Enterprise - Small Facility (estimated)

~$50,000–$80,000 (unconfirmed estimate)

per facility/year

✓EHR integration (Epic, Cerner) — claimed
✓Real-time patient deterioration alerts
✓Sepsis prediction module
✓Configurable alert thresholds
✓Dedicated implementation support

Enterprise - Mid-Size Facility (estimated)

~$80,000–$150,000 (unconfirmed estimate)

per facility/year

✓Everything in Small Facility tier
✓Capacity management dashboard
✓Advanced model calibration for local populations
✓Priority support and quarterly reviews

Enterprise - Large Hospital System (estimated)

~$150,000–$200,000+ (unconfirmed estimate)

per facility/year

✓Everything in Mid-Size tier
✓Multi-facility deployment and management console
✓Custom model tuning and ongoing optimization
✓Dedicated customer success manager
✓Enterprise SLA with 24/7 support

Pros & Cons

✅Pros

•Aims to consolidate deterioration detection, sepsis prediction, and capacity management into a single acute-care-focused platform, potentially reducing the need to procure and integrate multiple point solutions
•Claims direct integration into existing EHR workflows (Epic, Cerner) so clinicians don't need to learn a separate application
•Configurable alert sensitivity reportedly allows clinical informatics teams to tune the system to their facility's tolerance for alert fatigue
•Describes explainable risk scores showing contributing factors, which if validated would enable clinicians to make informed decisions rather than relying on black-box outputs
•Covers multiple acute care use cases within a single platform, unlike competitors that typically specialize in one domain (imaging, operations, or sepsis scoring alone)

❌Cons

•Independent verification of the product, its customer base, and clinical outcomes is extremely limited — no peer-reviewed studies, named references, or specific outcome data are publicly available
•Enterprise-only pricing (estimated at $50,000+/year based on comparable platforms) makes it inaccessible for small or rural hospitals without dedicated AI budgets
•As a newer entrant, Cleo lacks the established install base and track record of competitors like Qventus, Viz.ai, or Epic's native tools, increasing procurement risk
•Implementation requires a multi-week integration and calibration period, which may delay time-to-value by 2–3 months
•Limited to acute care settings — organizations looking for outpatient, primary care, or population health AI will need a separate solution
•FDA clearance status is not publicly documented, and no clinical validation studies are available in public databases such as PubMed

Who Should Use Cleo?

✓automation & workflows professionals
✓Teams needing collaboration features
✓Users who value advanced functionality

Who Should Skip Cleo?

×You need advanced features
×You're concerned about enterprise-only pricing (estimated at $50,000+/year based on comparable platforms) makes it inaccessible for small or rural hospitals without dedicated ai budgets
×You're concerned about as a newer entrant, cleo lacks the established install base and track record of competitors like qventus, viz.ai, or epic's native tools, increasing procurement risk

Our Verdict

⚠️

Cleo has potential but consider alternatives

Cleo offers useful features but may not be the best fit for everyone. Consider your specific needs and budget before deciding.

Try Cleo →Compare Alternatives →

Frequently Asked Questions

What is Cleo?

Is Cleo good?

Yes, Cleo is good for automation & workflows work. Users particularly appreciate aims to consolidate deterioration detection, sepsis prediction, and capacity management into a single acute-care-focused platform, potentially reducing the need to procure and integrate multiple point solutions. However, keep in mind independent verification of the product, its customer base, and clinical outcomes is extremely limited — no peer-reviewed studies, named references, or specific outcome data are publicly available.

How much does Cleo cost?

Cleo starts at ~$50,000–$80,000 (unconfirmed estimate). Check their pricing page for the most current rates and features included in each plan.

Who should use Cleo?

Cleo is ideal for automation & workflows professionals and teams who need reliable, feature-rich tools.

What are the best Cleo alternatives?

There are several automation & workflows tools available. Compare features, pricing, and user reviews to find the best option for your needs.

More about Cleo

Pricing Alternatives Free vs Paid Pros & Cons Worth It?Tutorial

📖 Cleo Overview 💰 Cleo Pricing 🆚 Free vs Paid 🤔 Is it Worth It?

Last verified March 2026

What is Cleo?

Key Features

Pricing Breakdown

Enterprise - Small Facility (estimated)

~$50,000–$80,000 (unconfirmed estimate)

per facility/year

✓EHR integration (Epic, Cerner) — claimed
✓Real-time patient deterioration alerts
✓Sepsis prediction module
✓Configurable alert thresholds
✓Dedicated implementation support

Enterprise - Mid-Size Facility (estimated)

~$80,000–$150,000 (unconfirmed estimate)

per facility/year

✓Everything in Small Facility tier
✓Capacity management dashboard
✓Advanced model calibration for local populations
✓Priority support and quarterly reviews

Enterprise - Large Hospital System (estimated)

~$150,000–$200,000+ (unconfirmed estimate)

per facility/year

✓Everything in Mid-Size tier
✓Multi-facility deployment and management console
✓Custom model tuning and ongoing optimization
✓Dedicated customer success manager
✓Enterprise SLA with 24/7 support

Pros & Cons

✅Pros

•Aims to consolidate deterioration detection, sepsis prediction, and capacity management into a single acute-care-focused platform, potentially reducing the need to procure and integrate multiple point solutions
•Claims direct integration into existing EHR workflows (Epic, Cerner) so clinicians don't need to learn a separate application
•Configurable alert sensitivity reportedly allows clinical informatics teams to tune the system to their facility's tolerance for alert fatigue
•Describes explainable risk scores showing contributing factors, which if validated would enable clinicians to make informed decisions rather than relying on black-box outputs
•Covers multiple acute care use cases within a single platform, unlike competitors that typically specialize in one domain (imaging, operations, or sepsis scoring alone)

❌Cons

•Independent verification of the product, its customer base, and clinical outcomes is extremely limited — no peer-reviewed studies, named references, or specific outcome data are publicly available
•Enterprise-only pricing (estimated at $50,000+/year based on comparable platforms) makes it inaccessible for small or rural hospitals without dedicated AI budgets
•As a newer entrant, Cleo lacks the established install base and track record of competitors like Qventus, Viz.ai, or Epic's native tools, increasing procurement risk
•Implementation requires a multi-week integration and calibration period, which may delay time-to-value by 2–3 months
•Limited to acute care settings — organizations looking for outpatient, primary care, or population health AI will need a separate solution
•FDA clearance status is not publicly documented, and no clinical validation studies are available in public databases such as PubMed

Who Should Skip Cleo?

×You need advanced features
×You're concerned about enterprise-only pricing (estimated at $50,000+/year based on comparable platforms) makes it inaccessible for small or rural hospitals without dedicated ai budgets
×You're concerned about as a newer entrant, cleo lacks the established install base and track record of competitors like qventus, viz.ai, or epic's native tools, increasing procurement risk

Frequently Asked Questions

What is Cleo?

Is Cleo good?

How much does Cleo cost?

Cleo starts at ~$50,000–$80,000 (unconfirmed estimate). Check their pricing page for the most current rates and features included in each plan.

Who should use Cleo?

Cleo is ideal for automation & workflows professionals and teams who need reliable, feature-rich tools.

What are the best Cleo alternatives?

There are several automation & workflows tools available. Compare features, pricing, and user reviews to find the best option for your needs.